Millions of papers on psychiatric & clinical neurosciences have been published worldwide and millions will continue to come out. Hundreds of brain diseases exist and the issue is to concretely put the pieces of a complex puzzle together to better understand them and hopefully treat them all one day. To succeed, the key is to bring lab researchers & clinicians close to each other and to enhance an innovative way on carrying out research on the brain through collaborative science. Lausanne is now amazingly well placed to meet this challenge. This is what our TEDxCHUV is all about.